It Happened One Night -- One of the best of the original early screwball comedies, it pairs up a handsome young Clark Gable with a lovely young Claudette Colbert in an impossible situation which would have never happened to any real people, but as with all the screwball comedies, wackiness ensues and ends in twoo love. It also single-handedly killed the undershirt industry in America when it was revealed that Gable didn't wear one.
My Cousin Vinny -- One of those movies I avoided like the plague cause it "looked dumb." Turned out to be hilarious, and I find myself watching it whenever it comes on (like it's doing right now on the Comedy Channel). It's really the only Joe Pesci film I like, and keep on the alert for a side-splittingly funny Fred Gwynn in one of his final roles.
Get Crazy -- I haven't seen this one since I was in college. Some friends made me watch it. I can't remember everything about it, but I do distinctly remember Malcolm McDowell as an aging, mildly insane rock star patterned loosely on Mick Jagger and Keith Richards combined into one. It's extremely hilarious and one should definitely NOT watch it before any other mildly serious film (such as Eraserhead).
Kiki's Delivery Service -- Top-notch Japanimation, early Studio Ghibli (Princess Mononoke, Spirited Away) production. One of the ones dubbed by Disney (with the voice of Phil Hartman in one of his final roles) and available on DVD. I saw a translation of it done by a good friend many, many years before Disney bought up the Ghibli catalog, and as I remember, the Disney translation is reasonably accurate and true to the original.